Chronic Venous Insufficiency (CVI) – Overview

Chronic Venous Insufficiency (CVI) is a persistent condition characterized by impaired blood circulation in the veins of the lower legs. It occurs when the valves or walls of the veins become weakened or damaged, causing blood to pool in the legs. This can lead to symptoms such as swelling, varicose veins, skin discoloration, and even the formation of leg ulcers. Risk factors commonly include prolonged periods of sitting or standing, obesity, aging, pregnancy, and a hereditary tendency toward venous disorders. While symptoms can vary in severity, they often involve a feeling of heaviness, cramping, pain, and swelling in the legs. Early diagnosis and prompt treatment are essential for managing the condition’s progression and enhancing patients' quality of life.

  Health   Apr 21, 2025   21  Add to Reading List
Chronic Venous Insufficiency (CVI) – Overview

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CVI Epidemiological Segmentation (2020–2034) – 7MM

Overall Prevalence of CVI

Prevalence by Gender

Prevalence by Age Group

Number of Treatable Cases

CVI Epidemiology (2023 Snapshot)

As of 2023, Chronic Venous Disease (CVD), which encompasses CVI, impacted approximately 463 million individuals across the seven major markets (7MM).

In the United States, around 6.2 million prevalent cases of CVI were reported.

In the US, the most commonly diagnosed stage of the disease was the C1 stage.

Epidemiological data reveals that the prevalence of CVI is higher in females and older adults, reflecting the condition's progressive nature.

CVI Market Overview

The CVI therapy and device market in the 7MM was valued at an estimated USD 2 billion in 2023.

Market Growth Drivers

The growing awareness of CVI and its related health issues is leading to increased adoption of advanced diagnostic and therapeutic solutions.

Continuous technological advancements, particularly in minimally invasive treatments like endovenous procedures and next-generation devices, are transforming care delivery.

Market Challenges

The high cost of advanced treatments and devices may restrict access, especially in healthcare systems with limited funding.

Encouraging patient adherence to lifestyle changes and compression therapy usage remains a significant challenge in effectively managing CVI.

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Emerging CVI Treatment Devices

  • VenoValve

  • EnVVe

  • SONOVEIN

  • Additional devices in development

Key Industry Players in the CVI Space

  • Philips

  • BD (Becton, Dickinson and Company)

  • Medtronic

  • Tactile Medical

  • Koya Medical

  • Verigraft AB

  • enVVeno Medical Corporation

  • Theraclion

  • Other key players

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